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Combined mean end-tidal isoflurane concentration for all dose levels was higher in dogs that received medetomidine, compared with ... JumptoContent JumptoMainNavigation Thissiteusescookies,tags,andtrackingsettingstostoreinformationthathelpgiveyoutheverybestbrowsingexperience. Dismissthiswarning AdvancedSearch Help JAVMA AJVR ABOUT JAVMASTAFF AJVRSTAFF SUBSCRIBE FAQs AUTHORS JAVMAINSTRUCTIONS AJVRINSTRUCTIONS COPYRIGHTTRANSFERFORM MANUSCRIPTSUBMISSION REVIEWERS JAVMAREVIEWERINFORMATION AJVRREVIEWERINFORMATION ADVERTISERS DISPLAYADS MEDIAKIT CLASSIFIEDADS Signin Signup Signin Signup JAVMA AJVR ABOUT JAVMASTAFF AJVRSTAFF SUBSCRIBE FAQs AUTHORS JAVMAINSTRUCTIONS AJVRINSTRUCTIONS COPYRIGHTTRANSFERFORM MANUSCRIPTSUBMISSION REVIEWERS JAVMAREVIEWERINFORMATION AJVRREVIEWERINFORMATION ADVERTISERS DISPLAYADS MEDIAKIT CLASSIFIEDADS REPRINTS/PERMISSIONS SEARCH AdvancedSearch Help   AmericanJournalofVeterinaryResearch ISSN: 0002-9645 PublicationDate: 01Jul2001 Volume62:Issue7 PublishedAheadofPrint Volume:82(2021) ShowItems Volume:81(2020) ShowItems Volume:80(2019) ShowItems Volume:79(2018) ShowItems Volume:78(2017) ShowItems Volume:77(2016) ShowItems Volume:76(2015) ShowItems Volume:75(2014) ShowItems Volume:74(2013) ShowItems Volume:73(2012) ShowItems Volume:72(2011) ShowItems Volume:71(2010) ShowItems Volume:70(2009) ShowItems Volume:69(2008) ShowItems Volume:68(2007) ShowItems Volume:67(2006) ShowItems Volume:66(2005) ShowItems Volume:65(2004) ShowItems Volume:64(2003) ShowItems Volume:63(2002) ShowItems Volume:62(2001) ShowItems Volume:61(2000) ShowItems Headings Abstract RelatedContent Effectsofrepetitionwithintrialsandfrequencyoftrialsessionsonquantitativeparametersofverticalforcepeakinhorseswithnaturallyoccurringlameness Authors MariKaido,AllisonH.Kilborne,JoyL.Sizemore,NathalieA.Reisbig,TuriK.Aarnes,andAliciaL.Bertone Influenceofrespiratorytractdiseaseandmodeofinhalationondetectabilityofbudesonideinequineurineandplasma Authors AnnKristinBarton,HenrikeHeinemann,InaSchenk,MarcMachnik,andHeidrunGehlen Effectoffentanylandlidocaineontheend-tidalsevofluraneconcentrationpreventingmotormovementindogs Authors MartinA.Suarez,RezaSeddighi,ChristineM.Egger,BartonW.Rohrbach,SherryK.Cox,ButchK.KuKanich,andThomasJ.Doherty Effectoforaladministrationofmeloxicampriortotransportoninflammatorymediatorsandleukoctyefunctionofcattleatfeedlotarrival Authors SarahF.Capik,BradJ.White,RobertL.Larson,NicholasVanEngen,NataliaCernicchiaro,TerryJ.Engelken,JeffreyLakritz,MichaelA.Ballou,LindseyE.Hulbert,RhondaC.Vann,JeffL.Caswell,GabriellaJacob,JefferyA.Carroll,andJohannF.Coetzee Effectsofrepeateduseandresterilizationonstructuralandfunctionalintegrityofmicrowaveablationantennas Authors CyrielleA.Finck,AlexR.zurLinden,AmeetSingh,RobertA.Foster,StephanieG.Nykamp,andWilliamC.Sears PreviousArticle NextArticle Comparisonofmedetomidine anddexmedetomidineaspremedicants indogsundergoingpropofol-isoflurane anesthesia ErjaKuusela DVM1,MarjaRaekallio DVM,PhD2,MisseVäisänen DVM3,KatjaMykkänen DVM4,HannuRopponen DVM5,andOutiVainio DVM,PhD6 ViewMore ViewLess 1 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. | 2 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. | 3 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. | 4 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. | 5 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. | 6 DepartmentofClinicalVeterinarySciences,Facultyof VeterinaryMedicine,UniversityofHelsinki,Helsinki,Finland. DOI: https://doi.org/10.2460/ajvr.2001.62.1073 Volume/Issue: Volume62:Issue7 OnlinePublicationDate: 01Jul2001 Restrictedaccess ReprintsandPermissions PurchaseArticle ABSTRACT/EXCERPT FULLTEXT Abstract Objective—Tocompare3doselevelsofmedetomidine anddexmedetomidineforuseaspremedicants indogsundergoingpropofol-isofluraneanesthesia. Animals—6healthyBeagles. Procedure—Dogsreceivedmedetomidineor dexmedetomidineintravenouslyatthefollowingdose levels:0.4µgofmedetomidineor0.2µgof dexmedetomidine/kgofbodyweight(M0.4/D0.2),4.0 µgofmedetomidineor2.0µgofdexmedetomidine/ kg(M4/D2),and40µgofmedetomidineor20µg ofdexmedetomidine/kg(M40/D20).Sedationand analgesiawerescoredbeforeinduction.Anesthesia wasinducedwithpropofolandmaintainedwith isoflurane.End-tidalisofluraneconcentration,heart rate,andarterialbloodpressuresandgaseswere measured. Results—Degreesofsedationandanalgesiawere significantlyaffectedbydoselevelbutnotdrug. Combinedmeanend-tidalisofluraneconcentrationfor alldoselevelswashigherindogsthatreceived medetomidine,comparedwithdexmedetomidine. Recoverytimewassignificantlyprolongedindogs treatedattheM40/D20doselevel,comparedwith theotherdoselevels.Afterinduction,bloodpressure decreasedbelowreferencerangeandheartrate increasedindogstreatedattheM0.4/D0.2dose level,whereasbloodpressurewaspreservedindogs treatedattheM40/D20doselevel.However,dogsin theselattergroupsdevelopedprofoundbradycardia andmildmetabolicacidosisduringanesthesia. TreatmentattheM4/D2doselevelresultedinmore stablecardiovasculareffects,comparedwiththe otherdoselevels.Inaddition,PaCO2wassimilar amongdoselevels. ConclusionsandClinicalRelevance—Dexmedetomidine isatleastassafeandeffectiveasmedetomidine foruseasapremedicantindogsundergoing propofol-isofluraneanesthesia.(AmJVetRes 2001;62:1073–1080) Abstract Objective—Tocompare3doselevelsofmedetomidine anddexmedetomidineforuseaspremedicants indogsundergoingpropofol-isofluraneanesthesia. Animals—6healthyBeagles. Procedure—Dogsreceivedmedetomidineor dexmedetomidineintravenouslyatthefollowingdose levels:0.4µgofmedetomidineor0.2µgof dexmedetomidine/kgofbodyweight(M0.4/D0.2),4.0 µgofmedetomidineor2.0µgofdexmedetomidine/ kg(M4/D2),and40µgofmedetomidineor20µg ofdexmedetomidine/kg(M40/D20).Sedationand analgesiawerescoredbeforeinduction.Anesthesia wasinducedwithpropofolandmaintainedwith isoflurane.End-tidalisofluraneconcentration,heart rate,andarterialbloodpressuresandgaseswere measured. Results—Degreesofsedationandanalgesiawere significantlyaffectedbydoselevelbutnotdrug. Combinedmeanend-tidalisofluraneconcentrationfor alldoselevelswashigherindogsthatreceived medetomidine,comparedwithdexmedetomidine. Recoverytimewassignificantlyprolongedindogs treatedattheM40/D20doselevel,comparedwith theotherdoselevels.Afterinduction,bloodpressure decreasedbelowreferencerangeandheartrate increasedindogstreatedattheM0.4/D0.2dose level,whereasbloodpressurewaspreservedindogs treatedattheM40/D20doselevel.However,dogsin theselattergroupsdevelopedprofoundbradycardia andmildmetabolicacidosisduringanesthesia. TreatmentattheM4/D2doselevelresultedinmore stablecardiovasculareffects,comparedwiththe otherdoselevels.Inaddition,PaCO2wassimilar amongdoselevels. ConclusionsandClinicalRelevance—Dexmedetomidine isatleastassafeandeffectiveasmedetomidine foruseasapremedicantindogsundergoing propofol-isofluraneanesthesia.(AmJVetRes 2001;62:1073–1080) Emailthiscontent ShareLink Copythislink,orclickbelowtoemailittoafriend Emailthiscontent orcopythelinkdirectly: https://avmajournals.avma.org/view/journals/ajvr/62/7/ajvr.2001.62.1073.xml Thelinkwasnotcopied.Yourcurrentbrowsermaynotsupportcopyingviathisbutton. 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